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Furthermore, PA could inhibit LPS-producing genus Helicobacter , and promote butyrate-producing genus Roseburia which revealed the protective effect of PA against NASH (Pham et al., 2022)

349 Similarly, Fusobacterium nucleatum activates TLR4/NF-B signaling and upregulates the antiapoptotic protein BIRC3, conferring resistance to 5-FU